Dr Janice Fullerton | Brain Sciences UNSW

Tabs

Main

University role:

Senior Research Scientist

Phone:

02 9399 1836

Email:

j.fullerton@unsw.edu.au

Dr Jan Fullerton is a Senior Research Scientist at NeuRA and a Conjoint Senior Lecturer at UNSW.

She completed her PhD in human genetics at The University of Melbourne in 2001. Dr Fullerton completed five years postdoctoral training at The Wellcome Trust Centre for Human Genetics, University of Oxford (UK), where she developed her career interest in psychiatric genetics and complex trait analysis. Here she studied the genetic contributors to personality, depression and anxiety in both humans and mice.

Dr Fullerton returned to Australia in 2006 on a NHMRC Howard Florey Fellowship, which allowed her to join NeuRA to study the genetics of major mental illnesses, with a particular focus on bipolar disorder. In 2013, Dr Fullerton was promoted to Group Leader, where she heads a number of projects in gene discovery using the latest genomics technologies, as well as projects examining the role of specific genes in risk of major psychiatric conditions.

Qualifications:

Doctor of Philosophy (Medicine): The University of Melbourne: Australia

Honours Degree (First Class): The University of Melbourne: Australia

Bachelor of Science: The University of Melbourne: Australia

Grants:

2019 NSW Health Biospecimen Collection Grant. 45 and Up Bipolar Study (EOI submitted 31 August 2018, invited for full application which was submitted 9 Dec 2018). Budget: $100,000

2017 UNSW Medicine Neuroscience, Mental Health and Addictions Theme and SPHERE Mindgardens CAG Collaborative Research Seed Funding “Establishing a Clinical Registry for Complex Mood Disorders” CIs: Colleen Loo, Philip B. Mitchell, Anthony Rodgers, Donel Martin, Samuel Harvey, David Berle, Janice Fullerton. ($40,000)

2017 NSW Health Office of Health and Medical Research - Sydney Collaborative Genomics “Genetic contributors, clinical course and pharmacogenomics of Bipolar Disorder using data linkage in NSW” CIs: Fullerton, Mitchell, Schofield, Havard, Toma, Maryanne O’Donnell. AIs: Green. ($2,460,000)

2017 NAB Foundation “Stronger Minds” grant: “Identification of mutant genes that contribute to bipolar disorder” CIs: A Cooper, JM Fullerton ($100,000)

2016 MLC Community Foundation – Whole Genome Sequencing of families with mental illness: 9 nuclear families with bipolar disorder. CI: A Cooper, Collaborator: JM Fullerton ($70,000)

2014 UNSW Major Equipment and Infrastructure Initiative “Life Technologies, Personal Genome Machine Benchtop Sequencer” CIs: CS Weickert, S Fillman, PR Schofield, P Sachdev, K Mather, JBJ Kwok, JM Fullerton, C Dobson-Stone, K Zavitsanou, S Fung, T Purves-Tyson ($162,598)

2014-2017 NHMRC project grant APP1063960 “Unravelling the genetic causes of bipolar disorder: lessons from rare but highly penetrant variants in very heritable forms of illness” CIA: JM Fullerton, CIB: PR Schofield ($684,890)

2014-2017 NHMRC project grant APP1066177 “The biology of risk for bipolar disorder: genetic effects in a high-risk longitudinal study” CIA: JM Fullerton, CIB: R Lenroot, CIC: JI Nurnberger Jr ($833,835)

2013-2014 Schizophrenia Research Institute 2013-2016 triennium Research Assistant funding ‘The role of sialyltransferase 8B in brain structural changes in schizophrenia’ ($35,000) CIA: J Fullerton, CIB AD Shaw

2013 UNSW Major Equipment and Infrastructure Initiative “Molecular and cell biology core equipment for new mental health, ageing and neurodegeneration research laboratories” CIs: PR Schofield, CS Weickert, JBJ Kwok, JM Fullerton, C Dobson-Stone, K Zavitsanou, S Fung, T Purves-Tyson, S Turner, T Karl, T Weickert ($140,790)

2012 UNSW Major Research Equipment & Infrastructure Grant “xCELLigence DP real time Cell Analysis System” CIs: V Catts, J Fullerton, K Sidhu, C Shannon Weickert ($65,000)

2011-2012 Schizophrenia Research Institute 2010-2013 triennium Research Officer funding ‘Investigation of the effects of genetic variation in the schizophrenia risk gene ST8SIA2 and differential effects of therapeutic treatment or lead exposure on neuronal migration in vitro’ ($105,000) CIA: J Fullerton, CIB PR Schofield

2010 UNSW Major Research Equipment and Infrastructure Initiative. CIs: C Dobson-Stone, JBJ Kwok, P Schofield, J Fullerton, P Sachdev ($64,300)

2010-2012 NHRMC project grant 630574 ($343,000) “Sialyltransferase in the bipolar and schizophrenic brain: examining the role of a novel generalised susceptibility gene” CIA: PR Schofield, CIB: J Fullerton, CIC: C Shannon Weickert, CID: JA Donald

2010-2011 NHRMC project grant 630452 ($293,000) “Neuregulin dependent neuronal migration and schizophrenia” CIA: C Shannon Weickert, CIB: B Garner, CIC: J Fullerton

2009 UNSW Faculty Research Grant (Faculty of Medicine): “Identification of genes that contribute to bipolar disorder by analysis of genetic epistasis.” CI: JM Fullerton. AI: PR Schofield ($20,000)

2008 Schizophrenia Research Institute: “The mechanism by which DNA variants in the NRG-1 gene lead to altered transcriptional regulation of NRG-1 isoforms in schizophrenia brains.” CIs: J Fullerton, J Kwok, C Shannon-Weickert, S Siva, P Schofield ($9000)

2006 UNSW Faculty of Medicine Strategic Research Initiatives: The Genetics Initiative CIs: Profs Schofield, Halliday, Mitchell, Sachdev Brodaty, Lloyd, Broe, Bryant, Dadds & Mattick, A/Profs Levy, Wilhelm & Teesson, Drs Kwok, Fullerton, Dobson-Stone, Chetcuti & Vollmer-Conna ($250,000)

Awards:

2014 Dean’s Rising Star Award, UNSW: “Significant contribution to research”.

2013 UNSW Silver star award CIA: J Fullerton, CIB: PR Schofield

2012 UNSW Gold star award CIA: J Fullerton, CIB: PR Schofield, CIC: JA Donald, CID: PB Mitchell

2010 UNSW Gold star award CIA: J Fullerton, CIB: PR Schofield, CIC: JA Donald, CID: PB Mitchell

2007 - 2008 NARSAD Young Investigator Award awarded by the National Alliance for Research on Schizophrenia and Depression, New York, USA (US$60,000). CI: J Fullerton, Sponsor: PR Schofield

2007 Brain Sciences UNSW 2007 Symposium Post-doctoral “Best Poster Award” awarded to J Fullerton

2005 – 2007 Howard Florey Centenary Research Fellowship awarded by the National Health and Medical Research Council, Australia. Grant #: 325643. CI: J Fullerton, Sponsor: PR Schofield

Research

Teaching & Supervision

I am available to supervise:

Yes

Currently supervising:

Sonia Hesam Shariati

Javad Jamshidi

Oliver Watkeys

Hayley North

Supervision keywords:

epigenomics

Publications related to this Person

Journal articles

Torrico B; Shaw A; Mosca R; Vivo-Luque N; Hervas A; Fernandez-Castillo N; Aloy P; Bayes M; Fullerton J; Cormand B, 2018, 'Truncating Variant Burden in High Functioning Autism and Pleiotropic Effects of LRP1 Across Psychiatric Phenotypes', Truncating Variant Burden in High Functioning Autism and Pleiotropic Effects of LRP1 Across Psychiatric Phenotypes, http://dx.doi.org/10.1101/429779

Nunes A; Schnack HG; Ching CRK; Agartz I; Akudjedu TN; Alda M; Alnæs D; Alonso-Lana S; Bauer J; Baune BT, 2018, 'Using structural MRI to identify bipolar disorders – 13 site machine learning study in 3020 individuals from the ENIGMA Bipolar Disorders Working Group', Molecular Psychiatry, http://dx.doi.org/10.1038/s41380-018-0228-9

Toma C; Pierce K; Shaw A; Heath A; Mitchell P; Schofield P; Fullerton J, 2018, 'Comprehensive cross-disorder analyses of CNTNAP2 suggest it is unlikely to be a primary risk gene for psychiatric disorders.', Comprehensive cross-disorder analyses of CNTNAP2 suggest it is unlikely to be a primary risk gene for psychiatric disorders., http://dx.doi.org/10.1101/363846

van Erp TGM; Walton E; Hibar DP; Schmaal L; Jiang W; Glahn DC; Pearlson GD; Yao N; Fukunaga M; Hashimoto R, 2018, 'Cortical Brain Abnormalities in 4474 Individuals With Schizophrenia and 5098 Control Subjects via the Enhancing Neuro Imaging Genetics Through Meta Analysis (ENIGMA) Consortium', Biological Psychiatry, vol. 84, pp. 644 - 654, http://dx.doi.org/10.1016/j.biopsych.2018.04.023

Anttila V; Bulik-Sullivan B; Finucane HK; Walters RK; Bras J; Duncan L; Escott-Price V; Falcone GJ; Gormley P; Malik R, 2018, 'Analysis of shared heritability in common disorders of the brain', Science, vol. 360, http://dx.doi.org/10.1126/science.aap8757

Kong XZ; Mathias SR; Guadalupe T; Abé C; Agartz I; Akudjedu TN; Aleman A; Alhusaini S; Allen NB; Ames D, 2018, 'Mapping cortical brain asymmetry in 17,141 healthy individuals worldwide via the ENIGMA consortium', Proceedings of the National Academy of Sciences of the United States of America, vol. 115, pp. E5154 - E5163, http://dx.doi.org/10.1073/pnas.1718418115

Tsai S-Y; Catts VS; Fullerton JM; Corley SM; Fillman SG; Weickert CS, 2018, 'Nuclear Receptors and Neuroinflammation in Schizophrenia.', Mol Neuropsychiatry, vol. 3, pp. 181 - 191, http://dx.doi.org/10.1159/000485565

Reinbold CS; Forstner AJ; Hecker J; Fullerton JM; Hoffmann P; Hou L; Heilbronner U; Degenhardt F; Adli M; Akiyama K, 2018, 'Analysis of the influence of microRNAs in lithium response in bipolar disorder', Frontiers in Psychiatry, vol. 9, http://dx.doi.org/10.3389/fpsyt.2018.00207

Toma C; Shaw AD; Allcock RJN; Heath A; Pierce KD; Mitchell PB; Schofield PR; Fullerton JM, 2018, 'An examination of multiple classes of rare variants in extended families with bipolar disorder', Translational Psychiatry, vol. 8, http://dx.doi.org/10.1038/s41398-018-0113-y

Hibar DP; Westlye LT; Doan NT; Jahanshad N; Cheung JW; Ching CRK; Versace A; Bilderbeck AC; Uhlmann A; Mwangi B, 2018, 'Cortical abnormalities in bipolar disorder: An MRI analysis of 6503 individuals from the ENIGMA Bipolar Disorder Working Group', Molecular Psychiatry, vol. 23, pp. 932 - 942, http://dx.doi.org/10.1038/mp.2017.73

Fullerton JM; Klauser P; Lenroot RK; Shaw AD; Overs B; Heath A; Cairns MJ; Atkins J; Scott R; Schofield PR, 2018, 'Differential effect of disease-associated ST8SIA2 haplotype on cerebral white matter diffusion properties in schizophrenia and healthy controls', Translational Psychiatry, vol. 8, http://dx.doi.org/10.1038/s41398-017-0052-z

Amare AT; Schubert KO; Hou L; Clark SR; Papiol S; Heilbronner U; Degenhardt F; Tekola-Ayele F; Hsu YH; Shekhtman T, 2018, 'Association of polygenic score for schizophrenia and HLA antigen and inflammation genes with response to lithium in bipolar affective disorder: A genome-wide association study', JAMA Psychiatry, vol. 75, pp. 65 - 74, http://dx.doi.org/10.1001/jamapsychiatry.2017.3433

Mühleisen TW; Reinbold CS; Forstner AJ; Abramova LI; Alda M; Babadjanova G; Bauer M; Brennan P; Chuchalin A; Cruceanu C, 2018, 'Gene set enrichment analysis and expression pattern exploration implicate an involvement of neurodevelopmental processes in bipolar disorder', Journal of Affective Disorders, vol. 228, pp. 20 - 25, http://dx.doi.org/10.1016/j.jad.2017.11.068

Chang H; Hoshina N; Zhang C; Ma Y; Cao H; Wang Y; Wu DD; Bergen SE; Landén M; Hultman CM, 2018, 'The protocadherin 17 gene affects cognition, personality, amygdala structure and function, synapse development and risk of major mood disorders', Molecular Psychiatry, vol. 23, pp. 400 - 412, http://dx.doi.org/10.1038/mp.2016.231

Corry J; Green M; Roberts G; Fullerton JM; Schofield PR; Mitchell PB, 2017, 'Does perfectionism in bipolar disorder pedigrees mediate associations between anxiety/stress and mood symptoms?', International Journal of Bipolar Disorders, vol. 5, http://dx.doi.org/10.1186/s40345-017-0102-8

Witt SH; Streit F; Jungkunz M; Frank J; Awasthi S; Reinbold CS; Treutlein J; Degenhardt F; Forstner AJ; Heilmann-Heimbach S, 2017, 'Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia', Translational psychiatry, vol. 7, pp. e1155, http://dx.doi.org/10.1038/tp.2017.115

van Hulzen KJE; Scholz CJ; Franke B; Ripke S; Klein M; McQuillin A; Sonuga-Barke EJ; Kelsoe JR; Landén M; Andreassen OA, 2017, 'Genetic Overlap Between Attention-Deficit/Hyperactivity Disorder and Bipolar Disorder: Evidence From Genome-wide Association Study Meta-analysis', Biological Psychiatry, vol. 82, pp. 634 - 641, http://dx.doi.org/10.1016/j.biopsych.2016.08.040

Wilcox HC; Fullerton JM; Glowinski AL; Benke K; Kamali M; Hulvershorn LA; Stapp EK; Edenberg HJ; Roberts GMP; Ghaziuddin N, 2017, 'Traumatic Stress Interacts With Bipolar Disorder Genetic Risk to Increase Risk for Suicide Attempts', Journal of the American Academy of Child and Adolescent Psychiatry, vol. 56, pp. 1073 - 1080, http://dx.doi.org/10.1016/j.jaac.2017.09.428

Hulvershorn LA; King J; Monahan PO; Wilcox HC; Mitchell PB; Fullerton JM; Edenberg HJ; Roberts GMP; Kamali M; Glowinski AL, 2017, 'Substance use disorders in adolescent and young adult relatives of probands with bipolar disorder: What drives the increased risk?', Comprehensive Psychiatry, vol. 78, pp. 130 - 139, http://dx.doi.org/10.1016/j.comppsych.2017.07.010

Klauser P; Baker ST; Cropley VL; Bousman C; Fornito A; Cocchi L; Fullerton JM; Rasser P; Schall U; Henskens F, 2017, 'White Matter Disruptions in Schizophrenia Are Spatially Widespread and Topologically Converge on Brain Network Hubs', Schizophrenia bulletin, vol. 43, pp. 425 - 435, http://dx.doi.org/10.1093/schbul/sbw100

Forstner AJ; Hecker J; Hofmann A; Maaser A; Reinbold CS; Mühleisen TW; Leber M; Strohmaier J; Degenhardt F; Treutlein J, 2017, 'Identification of shared risk loci and pathways for bipolar disorder and schizophrenia', PLoS ONE, vol. 12, http://dx.doi.org/10.1371/journal.pone.0171595

Chang H; Li L; Peng T; Grigoroiu-Serbanescu M; Bergen SE; Landén M; Hultman CM; Forstner AJ; Strohmaier J; Hecker J, 2017, 'Identification of a Bipolar Disorder Vulnerable Gene CHDH at 3p21.1', Molecular Neurobiology, vol. 54, pp. 5166 - 5176, http://dx.doi.org/10.1007/s12035-016-0041-x

Hou L; Bergen SE; Akula N; Song J; Hultman CM; Landén M; Adli M; Alda M; Ardau R; Arias B, 2016, 'Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder', Human Molecular Genetics, vol. 25, pp. 3383 - 3394, http://dx.doi.org/10.1093/hmg/ddw181

Li M; Luo XJ; Landén M; Bergen SE; Hultman CM; Li X; Zhang W; Yao YG; Zhang C; Liu J, 2016, 'Impact of a cis-associated gene expression SNP on chromosome 20q11.22 on bipolar disorder susceptibility, hippocampal structure and cognitive performance', British Journal of Psychiatry, vol. 208, pp. 128 - 137, http://dx.doi.org/10.1192/bjp.bp.114.156976

Hou L; Heilbronner U; Degenhardt F; Adli M; Akiyama K; Akula N; Ardau R; Arias B; Backlund L; Banzato CEM, 2016, 'Genetic variants associated with response to lithium treatment in bipolar disorder: A genome-wide association study', The Lancet, http://dx.doi.org/10.1016/S0140-6736(16)00143-4

Forstner AJ; Hofmann A; Maaser A; Sumer S; Khudayberdiev S; Mühleisen TW; Leber M; Schulze TG; Strohmaier J; Degenhardt F, 2015, 'Genome-wide analysis implicates microRNAs and their target genes in the development of bipolar disorder', Translational Psychiatry, vol. 5, http://dx.doi.org/10.1038/tp.2015.159

Fullerton JM; Koller DL; Edenberg HJ; Foroud T; Liu H; Glowinski AL; Mcinnis MG; Wilcox HC; Frankland A; Roberts G, 2015, 'Assessment of first and second degree relatives of individuals with bipolar disorder shows increased genetic risk scores in both affected relatives and young At-Risk Individuals', American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics, vol. 168, pp. 617 - 629, http://dx.doi.org/10.1002/ajmg.b.32344

Kamien B; Harraway J; Lundie B; Smallhorne L; Gibbs V; Heath A; Fullerton JM, 2015, 'Characterization of a 520kb deletion on chromosome 15q26.1 including ST8SIA2 in a patient with behavioral disturbance, autism spectrum disorder, and epilepsy: Additional information', American Journal of Medical Genetics, Part A, vol. 167, pp. 1424 - 1424, http://dx.doi.org/10.1002/ajmg.a.36846

Li M; Luo XJ; Rietschel M; Lewis CM; Mattheisen M; Müller-Myhsok B; Jamain S; Leboyer M; Landén M; Thompson PM, 2014, 'Allelic differences between Europeans and Chinese for CREB1 SNPs and their implications in gene expression regulation, hippocampal structure and function, and bipolar disorder susceptibility', Molecular Psychiatry, vol. 19, pp. 452 - 461, http://dx.doi.org/10.1038/mp.2013.37

Nurnberger JI; Koller DL; Jung J; Edenberg HJ; Foroud T; Guella I; Vawter MP; Kelsoe JR; Sklar P; Ripke S, 2014, 'Identification of pathways for bipolar disorder: A meta-analysis', JAMA Psychiatry, vol. 71, pp. 657 - 664, http://dx.doi.org/10.1001/jamapsychiatry.2014.176

Yuan Q; Rubic M; Seah J; Rae C; Wright IMR; Kaltenbach K; Feller JM; Abdel-Latif ME; Chu C; Oei JL, 2014, 'Do maternal opioids reduce neonatal regional brain volumes: A pilot study', Journal of Perinatology, vol. 34, pp. 909 - 913, http://dx.doi.org/10.1038/jp.2014.111

Shaw AD; Tiwari Y; Kaplan W; Heath A; Mitchell PB; Schofield PR; Fullerton JM, 2014, 'Characterisation of genetic variation in ST8SIA2 and its interaction region in NCAM1 in patients with bipolar disorder', PLoS ONE, vol. 9, http://dx.doi.org/10.1371/journal.pone.0092556

Joshi D; Fullerton JM; Weickert CS, 2014, 'Elevated ErbB4 mRNA is related to interneuron deficit in prefrontal cortex in schizophrenia', Journal of Psychiatric Research, vol. 53, pp. 125 - 132, http://dx.doi.org/10.1016/j.jpsychires.2014.02.014

Mühleisen TW; Leber M; Schulze TG; Strohmaier J; Degenhardt F; Treutlein J; Mattheisen M; Forstner AJ; Schumacher J; Breuer R, 2014, 'Genome-wide association study reveals two new risk loci for bipolar disorder', Nature Communications, vol. 5, http://dx.doi.org/10.1038/ncomms4339

Steinberg S; De Jong S; Mattheisen M; Costas J; Demontis D; Jamain S; Pietiläinen OPH; Lin K; Papiol S; Huttenlocher J, 2014, 'Common variant at 16p11.2 conferring risk of psychosis', Molecular Psychiatry, vol. 19, pp. 108 - 114, http://dx.doi.org/10.1038/mp.2012.157

Kamien B; Harraway J; Lundie B; Smallhorne L; Gibbs V; Heath A; Fullerton JM, 2013, 'Characterization of a 520kb deletion on chromosome 15q26.1 including ST8SIA2 in a patient with behavioral disturbance, autism spectrum disorder, and epilepsy', American Journal of Medical Genetics, Part A, http://dx.doi.org/10.1002/ajmg.a.36345

Dobson-Stone C; Luty AA; Thompson EM; Blumbergs P; Brooks WS; Short CL; Field CD; Panegyres PK; Hecker J; Solski JA, 2013, 'Frontotemporal dementia-amyotrophic lateral sclerosis syndrome locus on chromosome 16p12.1-q12.2: Genetic, clinical and neuropathological analysis', Acta Neuropathologica, vol. 125, pp. 523 - 533, http://dx.doi.org/10.1007/s00401-013-1078-9

Manchia M; Adli M; Akula N; Ardau R; Aubry JM; Backlund L; Banzato CEM; Baune BT; Bellivier F; Bengesser S, 2013, 'Assessment of Response to Lithium Maintenance Treatment in Bipolar Disorder: A Consortium on Lithium Genetics (ConLiGen) Report', PLoS ONE, vol. 8, http://dx.doi.org/10.1371/journal.pone.0065636

Hsu SC; Sears RL; Lemos RR; Quintáns B; Huang A; Spiteri E; Nevarez L; Mamah C; Zatz M; Pierce KD, 2013, 'Mutations in SLC20A2 are a major cause of familial idiopathic basal ganglia calcification', Neurogenetics, vol. 14, pp. 11 - 22, http://dx.doi.org/10.1007/s10048-012-0349-2

Sinclair D; Fullerton JM; Webster MJ; Weickert CS, 2012, 'Glucocorticoid receptor 1B and 1C mRNA transcript alterations in schizophrenia and bipolar disorder, and their possible regulation by GR gene variants', PLoS ONE, vol. 7, http://dx.doi.org/10.1371/journal.pone.0031720

Weickert CS; Tiwari Y; Schofield PR; Mowry BJ; Fullerton JM, 2012, 'Schizophrenia-associated HapICE haplotype is associated with increased NRG1 type III expression and high nucleotide diversity', Translational Psychiatry, vol. 2, http://dx.doi.org/10.1038/tp.2012.25

Sinclair D; Webster MJ; Fullerton JM; Weickert CS, 2012, 'Glucocorticoid receptor mRNA and protein isoform alterations in the orbitofrontal cortex in schizophrenia and bipolar disorder', BMC Psychiatry, vol. 12, http://dx.doi.org/10.1186/1471-244X-12-84

Li M; Wang Y; Zheng XB; Ikeda M; Iwata N; Luo XJ; Chong SA; Lee J; Rietschel M; Zhang F, 2012, 'Meta-analysis and brain imaging data support the involvement of VRK2 (rs2312147) in schizophrenia susceptibility', Schizophrenia Research, vol. 142, pp. 200 - 205, http://dx.doi.org/10.1016/j.schres.2012.10.008

McAuley EZ; Scimone A; Tiwari Y; Agahi G; Mowry BJ; Holliday EG; Donald JA; Weickert CS; Mitchell PB; Schofield PR, 2012, 'Identification of sialyltransferase 8B as a generalized susceptibility gene for psychotic and mood disorders on chromosome 15q25-26', PLoS ONE, vol. 7, http://dx.doi.org/10.1371/journal.pone.0038172

Sklar P; Ripke S; Scott LJ; Andreassen OA; Cichon S; Craddock N; Edenberg HJ; Nurnberger JI; Rietschel M; Blackwood D, 2011, 'Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4', Nature Genetics, vol. 43, pp. 977 - 985, http://dx.doi.org/10.1038/ng.943

Fullerton JM; Tiwari Y; Agahi G; Heath A; Berk M; Mitchell PB; Schofield PR, 2010, 'Assessing oxidative pathway genes as risk factors for bipolar disorder', Bipolar Disorders, vol. 12, pp. 550 - 556, http://dx.doi.org/10.1111/j.1399-5618.2010.00834.x

Mitchell PB; Meiser B; Wilde A; Fullerton J; Donald J; Wilhelm K; Schofield PR, 2010, 'Predictive and diagnostic genetic testing in psychiatry', Psychiatric Clinics of North America, vol. 33, pp. 225 - 243, http://dx.doi.org/10.1016/j.psc.2009.10.001

Fullerton JM; Donald JA; Mitchell PB; Schofield PR, 2010, 'Two-Dimensional Genome Scan Identifies Multiple Genetic Interactions in Bipolar Affective Disorder', Biological Psychiatry, vol. 67, pp. 478 - 486, http://dx.doi.org/10.1016/j.biopsych.2009.10.022

McAuley EZ; Blair IP; Liu Z; Fullerton JM; Scimone A; Van Herten M; Evans MR; Kirkby KC; Donald JA; Mitchell PB, 2009, 'A genome screen of 35 bipolar affective disorder pedigrees provides significant evidence for a susceptibility locus on chromosome 15q25-26', Molecular Psychiatry, vol. 14, pp. 492 - 500, http://dx.doi.org/10.1038/sj.mp.4002146

Fullerton JM; Willis-Owen SAG; Yalcin B; Shifman S; Copley RR; Miller SR; Bhomra A; Davidson S; Oliver PL; Mott R, 2008, 'Human-Mouse Quantitative Trait Locus Concordance and the Dissection of a Human Neuroticism Locus', Biological Psychiatry, vol. 63, pp. 874 - 883, http://dx.doi.org/10.1016/j.biopsych.2007.10.019

Mitchell PB; Fullerton J; Donald J; Schofield PR, 2008, 'Two-dimensional genome scan identifies complex epistatic interactions in bipolar disorder', BIPOLAR DISORDERS, vol. 10, pp. 15 - 15, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000252711100037&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Fullerton JM; Liu Z; Badenhop RF; Scimone A; Blair IP; Van Herten M; Donald JA; Mitchell PB; Schofield PR, 2008, 'Genome screen of 15 Australian bipolar affective disorder pedigrees supports previously identified loci for bipolar susceptibility genes', Psychiatric Genetics, vol. 18, pp. 156 - 161, http://dx.doi.org/10.1097/YPG.0b013e3282fa1861

McAuley EZ; Fullerton JM; Blair IP; Donald JA; Mitchell PB; Schofield PR, 2007, 'Association between the serotonin 2A receptor gene and bipolar affective disorder in an Australian cohort', Plastic Surgical Nursing, vol. 19, pp. 244 - 252, http://dx.doi.org/10.1097/YPG.0b013e32832ceea9

Fullerton J; Heath A; Mitchell P; Schofield P, 2006, 'Investigation of circadian disruption in bipolar disorder.', Acta Neuropsychiatr, vol. 18, pp. 251, http://dx.doi.org/10.1017/S0924270800030283

Schofield PR; Blair IP; Chetcuti A; McAuley EZ; Fullerton JM; Donald JA; Mitchell PB, 2006, '03-04 Genetic and genomic approaches to better understanding bipolar disorder.', Acta Neuropsychiatr, vol. 18, pp. 321, http://dx.doi.org/10.1017/S0924270800032038

Fullerton J, 2006, 'New approaches to the genetic analysis of neuroticism and anxiety', Behavior Genetics, vol. 36, pp. 147 - 161, http://dx.doi.org/10.1007/s10519-005-9000-4

Willis-Owen SAG; Fullerton J; Surtees PG; Wainwright NWJ; Miller S; Flint J, 2005, 'The Val66Met coding variant of the brain-derived neurotrophic factor (BDNF) gene does not contribute toward variation in the personality trait neuroticism', Biological Psychiatry, vol. 58, pp. 738 - 742, http://dx.doi.org/10.1016/j.biopsych.2005.05.014

Yalcin B; Fullerton J; Miller S; Keays DA; Brady S; Bhomra A; Jefferson A; Volpi E; Copley RR; Flint J, 2004, 'Unexpected complexity in the haplotypes of commonly used inbred strains of laboratory mice', Proceedings of the National Academy of Sciences of the United States of America, vol. 101, pp. 9734 - 9739, http://dx.doi.org/10.1073/pnas.0401189101

Khoo JP; Nicoli T; Alp NJ; Fullerton J; Flint J; Channon KM, 2004, 'Congenic mapping and genotyping of the tetrahydrobiopterin-deficient hph-1 mouse', Molecular Genetics and Metabolism, vol. 82, pp. 251 - 254, http://dx.doi.org/10.1016/j.ymgme.2004.04.006

Yalcin B; Willis-Owen SAG; Fullerton J; Meesaq A; Deacon RM; Rawlins JNP; Copley RR; Morris AP; Flint J; Mott R, 2004, 'Genetic dissection of a behavioral quantitative trait locus shows that Rgs2 modulates anxiety in mice', Nature Genetics, vol. 36, pp. 1197 - 1202, http://dx.doi.org/10.1038/ng1450

Talbot CJ; Radcliffe RA; Fullerton J; Hitzemann R; Wehner JM; Flint J, 2003, 'Fine scale mapping of a genetic locus for conditioned fear', Mammalian Genome, vol. 14, pp. 223 - 230, http://dx.doi.org/10.1007/s00335-002-3059-5

Fullerton J; Cubin M; Tiwari H; Wang C; Bomhra A; Davidson S; Miller S; Fairburn C; Goodwin G; Neale MC, 2003, 'Linkage analysis of extremely discordant and concordant sibling pairs identifies quantitative-trait loci that influence variation in the human personality trait neuroticism', American Journal of Human Genetics, vol. 72, pp. 879 - 890, http://dx.doi.org/10.1086/374178

Fullerton J; Paprocki P; Foote S; Mackey DA; Williamson R; Forrest S, 2002, 'Identity-by-descent approach to gene localisation in eight individuals affected by keratoconus from north-west Tasmania, Australia.', Hum Genet, vol. 110, pp. 462 - 470, http://dx.doi.org/10.1007/s00439-002-0705-7

Forrest S; Dunn K; Elliott K; Fitzpatrick E; Fullerton J; McCarthy M; Brown J; Hill D; Williamson R, 1999, 'Identifying genes predisposing to atopic eczema.', J Allergy Clin Immunol, vol. 104, pp. 1066 - 1070, https://www.ncbi.nlm.nih.gov/pubmed/10550754

Conference Papers

Boss P; Loo C; Fullerton J; Mitchell P, 2019, 'The Genes, Clinical Assessment and Depression (GLAD) study', in BIPOLAR DISORDERS, WILEY, Sydney, AUSTRALIA, pp. 137 - 138, presented at 21st Annual ISBD Conference on Global Advances in Bipolar Disorder and Depression, Sydney, AUSTRALIA, 20 - 23 March 2019, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000461513600304&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Toma C; Shaw AD; Allcock R; Mitchell PB; Schofield PR; Fullerton JM, 2017, 'ADDRESSING RARE VARIANT CONTRIBUTIONS TO THE GENETIC ARCHITECTURE OF BIPOLAR DISORDER, UTILIZING EXTENDED FAMILIES WITH HIGHLY PENETRANT FORMS OF ILLNESS', in EUROPEAN NEUROPSYCHOPHARMACOLOGY, ELSEVIER SCIENCE BV, Toronto, CANADA, pp. S293 - S293, presented at 23rd Annual World Congress of Psychiatric Genetics (WCPG), Toronto, CANADA, 16 - 20 October 2015, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000413843800365&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Fullerton J; Klauser P; Lenroot R; Shaw A; Heath A; Cairns M; Scotts R; Schofield P; Weickert CS; Pantellis C, 2017, 'DIFFERENTIAL EFFECTS OF DISEASE ASSOCIATED ST8SIA2 HAPLOTYPE ON CORTICAL WHITE MATTER IN SCHIZOPHRENIA', in EUROPEAN NEUROPSYCHOPHARMACOLOGY, ELSEVIER SCIENCE BV, Toronto, CANADA, pp. S237 - S238, presented at 23rd Annual World Congress of Psychiatric Genetics (WCPG), Toronto, CANADA, 16 - 20 October 2015, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000413843800261&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Nurnberger JI; Wilcox H; Glowinsky A; Mitchell P; Fullerton J; Hulvershorn L; Kamali M; Ghaziuddin N; Koller D; Foroud T, 2015, 'Combined use of clinical and genetic information in the prediction of risk for bipolar disorder', in BIPOLAR DISORDERS, WILEY-BLACKWELL, pp. 11 - 11, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000355338100012&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Nurnberger J; McInnis M; Wilcox H; Glowinski A; Mitchell P; Fullerton J; Hulvershorn L; Kamali M; Ghiazuddin N; Koller D, 2015, 'Combined Use of Clinical and Genetic Information in the Prediction of Risk for Bipolar Disorder', in BIOLOGICAL PSYCHIATRY, ELSEVIER SCIENCE INC, Toronto, CANADA, presented at 70th Annual Scientific Meeting of the Society-of-Biological-Psychiatry on Stress, Emotion, Neurodevelopment and Psychopathology, Toronto, CANADA, 14 - 16 May 2015, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000352207501029&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Fullerton J; lenroot R; roberts G; overs B; frankland A; schofield P; mitchell P, 2015, 'Neurodevelopmental Trajectories in Young People at High Familial Risk for Bipolar Disorder', in European Neuropsychopharmacology, XXIIIrd World Congress of Psychiatric Genetics, Toronto, presented at XXIIIrd World Congress of Psychiatric Genetics, Toronto, 28 - 31 October 2015, http://dx.doi.org/10.1016/j.euroneuro.2015.09.009

Mitchell P; Roberts G; Frankland A; Breakspear M; Schofield P; Fullerton J, 2014, 'Using brain imaging and genetics to identify those at high risk for bipolar disorder', in INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, CAMBRIDGE UNIV PRESS, Vancouver, CANADA, pp. 14 - 14, presented at 29th CINP World Congress of Neuropsychopharmacology, Vancouver, CANADA, 22 - 26 June 2014, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000339769200054&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Anderson-Schmidt H; Beltcheva O; Brandon MD; Byrne EM; Diehl EJ; Duncan L; Gonzalez SD; Hannon E; Kantojärvi K; Karagiannidis I, 2013, 'Selected rapporteur summaries from the XX World Congress of Psychiatric Genetics, Hamburg, Germany, October 14-18, 2012.', in Am J Med Genet B Neuropsychiatr Genet, United States, pp. 96 - 121, United States, http://dx.doi.org/10.1002/ajmg.b.32132

Schofield PR; Fullerton JM; Gatt JM; Williams LM; Mitchell PB, 2013, 'Genetic approaches to understanding the etiology of mood disorders', in JOURNAL OF MOLECULAR NEUROSCIENCE, HUMANA PRESS INC, Eilat, ISRAEL, pp. S107 - S107, presented at 21st Annual Meeting of the Israel-Society-for-Neuroscience / 1st Binational Australian-Israeli Meeting on Neuroscience, Eilat, ISRAEL, 15 - 15 December 2012, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000332833800274&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Mitchell P; Roberts G; Fullerton JM; Green M; Breakspear M; Frankland A; Levy F; Lenroot R; Wen W; Lau P, 2013, 'Imaging and genetic studies in youth at high risk for bipolar disorder', in BIPOLAR DISORDERS, WILEY-BLACKWELL, Miami Beach, FL, pp. 41 - 41, presented at 10th International Conference on Bipolar Disorder of the International-Society-for-Bipolar-Disorders, Miami Beach, FL, 13 - 16 June 2013, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000319826800087&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Weickert CS; Tiwari Y; Schofield PR; Fullerton JM, 2011, 'Linking the NRG1-realted Genetic Risk of Schizophrenia to Increased Type III NRG1 mRNA', in BIOLOGICAL PSYCHIATRY, ELSEVIER SCIENCE INC, San Francisco, CA, pp. 13S - 13S, presented at 66th Annual Meeting of the Society-of-Biological-Psychiatry, San Francisco, CA, 12 - 14 May 2011, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000290641800043&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Fullerton JM; Tiwari Y; Schofield PR; Weickert CS, 2010, 'INCREASED FREQUENCY OF NOVEL NRG1 GENE VARIANTS IN SCHIZOPHRENIA AND THE EFFECT OF NUCLEOTIDE VARIATION ON MRNA ISOFORM TRANSCRIPTIONAL REGULATION', in SCHIZOPHRENIA RESEARCH, ELSEVIER SCIENCE BV, Florence, ITALY, pp. 334 - 335, presented at 2nd Conference of the Schizophrenia-International-Research-Society (SIRS), Florence, ITALY, 10 - 14 April 2010, http://dx.doi.org/10.1016/j.schres.2010.02.576

McAuley EZ; Blair IP; Fullerton JM; Donald JA; Mitchell PB; Schofield PR, 2006, 'Identification of a bipolar disorder susceptibility locus on chromosome 15Q', in AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS, WILEY-LISS, Cagliari, ITALY, pp. 695 - 696, presented at 14th World Congress on Psychiatric Genetics, Cagliari, ITALY, 28 October - 01 November 2006, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000240877700051&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

McAuley E; Blair I; Fullerton J; Donald J; Mitchell P; Schofield P, 2006, 'Identification of a bipolar disorder susceptibility locus on chromosome 15Q.', in Acta Neuropsychiatr, England, pp. 261, England, http://dx.doi.org/10.1017/S0924270800030544

Willis-Owen S; Yalcin B; Fullerton J; Meesaq A; Deacon R; Rawlins N; Copley R; Morris A; Flint J; Mott R, 2005, 'Finding quantitative trait genes that influence mouse behaviour - and investigating their role in human psychopathology', in AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS, WILEY-LISS, Boston, MA, pp. 94 - 95, presented at 13th World Congress on Psychiatric Genetics, Boston, MA, 04 - 08 September 2005, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000232357300338&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Fullerton J; Brady S; Cubin M; Tiwari H; Wang CX; Bomhra A; Davidson S; Miller S; Fairburn C; Goodwin G, 2004, 'Molecular approaches to identifying candidate genes in depression', in BEHAVIOR GENETICS, SPRINGER, Aix en Provence, FRANCE, pp. 639 - 639, presented at 34th Annual Meeting of the Behavior-Genetics-Association, Aix en Provence, FRANCE, 27 - 30 June 2004, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000224808200039&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Fullerton J; Cubin M; Bhomra A; Davidson S; Miller S; Turn M; Dolby C; Mott R; Wang C; Tiwari H, 2002, 'Linkage analysis of extremely discordant and concordant sibling pairs identifies QTL that influence variation in a human personality trait.', in AMERICAN JOURNAL OF HUMAN GENETICS, UNIV CHICAGO PRESS, BALTIMORE, MARYLAND, pp. 216 - 216, presented at 52nd Annual Meeting of the American-Society-of-Human-Genetics, BALTIMORE, MARYLAND, 15 - 19 October 2002, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000178025800265&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Fullerton JM; Paprocki P; Foote S; Mackie D; Williamson R; Forrest S, 1999, 'An association approach using eight affected individuals from Tasmania, Australia maps a locus for keratoconus.', in AMERICAN JOURNAL OF HUMAN GENETICS, UNIV CHICAGO PRESS, pp. A31 - A31, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000082879800159&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Conference Presentations

Lenroot RK; Roberts G; Fullerton J; Overs B; Schofield P; Mitchell P, 2015, 'BIPOLAR DISORDER KIDS & SIBS STUDY: NEUROIMAGING FINDINGS IN YOUNG PEOPLE AT HIGH RISK FOR BIPOLAR DISORDER', in AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY, SAGE PUBLICATIONS LTD, Vol. 49, pp. 82 - 82, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000354437500206&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Conference Abstracts

Weickert CS; Fullerton JM; Hu S; Kyaw M; Schofield PR; Carr VJ; Laughlin C; Schall U; Scott RJ; Jablensky AV, 2016, 'SCHIZOPHRENIA AND COGNITIVE DYSFUNCTION ASSOCIATED WITH THE ESTROGEN RECEPTOR 1 GENOTYPE', in AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY, SAGE PUBLICATIONS LTD, Vol. 50, pp. 77 - 77, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000375591600173&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Jahanshad N; Kochunov P; Armstrong N; Bastin M; Bearden C; Brouwer R; Cannon D; Caseras X; Costa Rica - Colombia Bipolar Consortium; Crespo-Facorro B, 2015, 'Meta-analyzing genome-wide associations with white matter microstructure - the ENIGMA-DTI group [Poster abstract 3407]', in Proceedings of the 21st Annual Meeting of the Organization for Human Brain Mapping (OHBM), 21st Annual Meeting of the Organization for Human Brain Mapping (OHBM), Honolulu, Hawaii, USA, presented at 21st Annual Meeting of the Organization for Human Brain Mapping (OHBM), Honolulu, Hawaii, USA, 14 - 18 June 2015

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