Associate Professor Thomas Fath | Brain Sciences UNSW

Tabs

Main

University role:

Conjoint Associate Professor

Phone:

+61 2 9385 9690

Email:

t.fath@unsw.edu.au

Research Interests:
The primary research focus of the lab is on the regulation of the cytoskeleton in injury and diseases of the central nervous system, including brain trauma, Alzheimer's Disease and motor neuron disease. For this, we employ cell and tissue cultures and genetically modified mice, combined with advanced imaging technologies. Recent outcome from our work demonstrates that distinct isoforms of the tropomyosin protein family regulate early processes of neuronal morphogenesis and that these proteins are key regulators of the cellular architecture in sub-cellular compartments of neuronal cells such as the growth cones of extending neurites in the developing and synaptic connections in the mature nervous system. Our research team investigates the actin cytoskeleton as potential drug target to provide protection and promote regeneration in the injured or diseased nervous system.

For current PhD project opportunities and scholarships:
Visit: http://www.2025.unsw.edu.au/apply => UNSW Scientia PhD Scholarship and select 'Mindgardens - Molecular Neuroscience' as Strategic Area; Project: 'Manipulation of the synaptic actin cytoskeleton as novel therapeutic approach'

Broad Research Areas:
Neuroscience, Neurodegenerative Diseases, Motor Neuron Disease, Cell Biology and Gene Regulation, Disease Modelling, Injury

Qualifications:
PhD

Society Memberships & Professional Activities:
American Society for Cell Biology, Society for Neuroscience, Australasian Neuroscience Society, Australian and New Zealand Society for Cell and Developmental Biology

Specific Research Keywords:
Cytoskeleton, Central nervous system disease injury and repair, Cell Biology, Alzheimer's Disease, Amyotrophic Lateral Sclerosis, Neurodevelopment

ORCID ID:
orcid.org/0000-0002-6877-7567

Grants:

NHMRC Project Grant: 'Targeting the synaptic actin cytoskeleton in Alzheimer's disease' [2015-2018]

NHMRC Project Grant: 'Restoring neuroprotective sphingosine 1-phosphate signalling in Alzheimer's disease' [2016-2019]

Keywords:

alzheimer disease

dementia

actin cytoskeleton

nerve regeneration

neurites

motor neuron disease

tropomyosin

Research

Teaching & Supervision

I am available to supervise:

Yes

Areas of supervision:

PhD projects in the field of Alzheimer's disease and Neurite regeneration available.

Currently supervising:

Alexandra Suchowerska (PhD candidate, Field of Research: Alzheimer's disease)

Tamara Tomanic (PhD candidate, Field of Research: Alzheimer's disease)

Merryn Brettle (PhD candidate, Field of Research: Motor neuron disease)

Chanchanok Chaichim (PhD candidate, joint supervisor, Field of Research: Alzheimer's disease)

Supervision keywords:

nervous system diseases

brain

mice

tissue culture

Engagement

New South Wales State Representative, Australasian Neuroscience Society (ANS)

Organizer, Annual Brain Awareness week at UNSW

Publications related to this Person

Book Chapters

Polly P; Vickery R; Thai T; Yang JL; Fath T; Herbert C; Jones N; Lewis T; Pather N; Schibeci S, 2016, 'ePortfolios, assessment and professional skills in the medical sciences', in ePortfolios in Australian Universities, pp. 47 - 64, http://dx.doi.org/10.1007/978-981-10-1732-2_4

Craig AJ; Housley GD; Fath T, 2014, 'Modeling excitotoxic ischemic brain injury of cerebellar purkinje neurons by intravital and in vitro multi-photon laser scanning microscopy', in Neuromethods, pp. 105 - 127, http://dx.doi.org/10.1007/978-1-4939-0381-8_5

Curthoys NM; Gunning PW; Fath T, 2011, 'Tropomyosins in Neuronal Morphogenesis and Development', in Nixon RA; Yuan A (ed.), CYTOSKELETON OF THE NERVOUS SYSTEM, edn. Advances in Neurobiology, SPRINGER, pp. 411 - 445, http://dx.doi.org/10.1007/978-1-4419-6787-9_18

Journal articles

Fröhlich D; Suchowerska AK; Voss C; He R; Wolvetang E; Von Jonquieres G; Simons C; Fath T; Housley GD; Klugmann M, 2018, 'Expression pattern of the aspartyl-tRNA synthetase DARS in the human brain', Frontiers in Molecular Neuroscience, vol. 11, http://dx.doi.org/10.3389/fnmol.2018.00081

Stefen H; Suchowerska AK; Chen BJ; Brettle M; Kuschelewski J; Gunning PW; Janitz M; Fath T, 2018, 'Tropomyosin isoforms have specific effects on the transcriptome of undifferentiated and differentiated B35 neuroblastoma cells', FEBS Open Bio, vol. 8, pp. 570 - 583, http://dx.doi.org/10.1002/2211-5463.12386

Tonkin RS; Bowles C; Perera CJ; Keating BA; Makker PGS; Duffy SS; Lees JG; Tran C; Don AS; Fath T, 2018, 'Attenuation of mechanical pain hypersensitivity by treatment with Peptide5, a connexin-43 mimetic peptide, involves inhibition of NLRP3 inflammasome in nerve-injured mice', Experimental Neurology, vol. 300, pp. 1 - 12, http://dx.doi.org/10.1016/j.expneurol.2017.10.016

Fath T; Kostyukova AS; Foa L, 2017, 'Special issue on ‘Cytoskeleton-dependent regulation of neuronal network formation’', Molecular and Cellular Neuroscience, vol. 84, pp. 1 - 3, http://dx.doi.org/10.1016/j.mcn.2017.09.008

Suchowerska AK; Fok S; Stefen H; Gunning PW; Hardeman EC; Power J; Fath T, 2017, 'Developmental profiling of tropomyosin expression in mouse brain reveals Tpm4.2 as the major post-synaptic tropomyosin in the mature brain', Frontiers in Cellular Neuroscience, vol. 11, http://dx.doi.org/10.3389/fncel.2017.00421

Patel S; Fok SYY; Stefen H; Tomanić T; Parić E; Herold R; Brettle M; Djordjevic A; Fath T, 2017, 'Functional characterisation of filamentous actin probe expression in neuronal cells', PLoS ONE, vol. 12, http://dx.doi.org/10.1371/journal.pone.0187979

Bi M; Gladbach A; Van Eersel J; Ittner A; Przybyla M; Van Hummel A; Chua SW; Hoven JVD; Lee WS; Müller J, 2017, 'Tau exacerbates excitotoxic brain damage in an animal model of stroke', Nature Communications, vol. 8, http://dx.doi.org/10.1038/s41467-017-00618-0

Gormal R; Valmas N; Fath T; Meunier F, 2017, 'A role for tropomyosins in activity-dependent bulk endocytosis?', Molecular and Cellular Neuroscience, vol. 84, pp. 112 - 118, http://dx.doi.org/10.1016/j.mcn.2017.04.003

Gray KT; Kostyukova AS; Fath T, 2017, 'Actin regulation by tropomodulin and tropomyosin in neuronal morphogenesis and function', Molecular and Cellular Neuroscience, vol. 84, pp. 48 - 57, http://dx.doi.org/10.1016/j.mcn.2017.04.002

Fröhlich D; Suchowerska AK; Spencer ZHT; von Jonquieres G; Klugmann CB; Bongers A; Delerue F; Stefen H; Ittner LM; Fath T, 2017, 'In vivo characterization of the aspartyl-tRNA synthetase DARS: Homing in on the leukodystrophy HBSL', Neurobiology of Disease, vol. 97, pp. 24 - 35, http://dx.doi.org/10.1016/j.nbd.2016.10.008

Yang JL; Polly P; Fath T; Jones N; Power J, 2016, 'ISA model and integrative career development learning in year three science courses', International Journal of Science, Mathematics and Technology Learning, vol. 23, pp. 33 - 49

Tate MLK; Fath T, 2016, 'The Only Constant Is Change: Next Generation Materials and Medical Device Design for Physical and Mental Health', Advanced Healthcare Materials, vol. 5, pp. 1840 - 1843, http://dx.doi.org/10.1002/adhm.201600437

Brettle M; Patel S; Fath T, 2016, 'Tropomyosins in the healthy and diseased nervous system', Brain Research Bulletin, vol. 126, pp. 311 - 323, http://dx.doi.org/10.1016/j.brainresbull.2016.06.004

Gray KT; Suchowerska AK; Bland T; Colpan M; Wayman G; Fath T; Kostyukova AS, 2016, 'Tropomodulin isoforms utilize specific binding functions to modulate dendrite development', Cytoskeleton, http://dx.doi.org/10.1002/cm.21304

Couttas TA; Kain N; Suchowerska AK; Quek LE; Turner N; Fath T; Garner B; Don AS, 2016, 'Loss of ceramide synthase 2 activity, necessary for myelin biosynthesis, precedes tau pathology in the cortical pathogenesis of Alzheimer's disease', Neurobiology of Aging, vol. 43, pp. 89 - 100, http://dx.doi.org/10.1016/j.neurobiolaging.2016.03.027

Stefen H; Chaichim C; Power J; Fath T, 2016, 'Regulation of the Postsynaptic Compartment of Excitatory Synapses by the Actin Cytoskeleton in Health and Its Disruption in Disease', Neural Plasticity, vol. 2016, http://dx.doi.org/10.1155/2016/2371970

An H; Brettle M; Lee T; Heng B; Lim CK; Guillemin GJ; Lord MS; Klotzsch E; Geczy CL; Bryant K, 2016, 'Soluble LILRA3 promotes neurite outgrowth and synapses formation through a high-affinity interaction with Nogo 66', Journal of Cell Science, vol. 129, pp. 1198 - 1209, http://dx.doi.org/10.1242/jcs.182006

Sytnyk V; Fath T, 2015, 'Synapse Function in Dementia and Neurodegenerative Disorders', Australian Biochemist, vol. 46, https://www.asbmb.org.au/magazine/2015_April_Issue46-1/Showcase%204%20-%20Fath.pdf

Brettle M; Suchowerska AK; Chua SW; Ittner LM; Fath T, 2015, 'Amyotrophic lateral sclerosis-associated mutant profilin 1 increases dendritic arborisation and spine formation in primary hippocampal neurons', Neuroscience Letters, vol. 609, pp. 223 - 228, http://dx.doi.org/10.1016/j.neulet.2015.09.034

Schevzov G; Kee AJ; Wang B; Sequeira VB; Hook J; Coombes JD; Lucas CA; Stehn JR; Musgrove EA; Cretu A, 2015, 'Regulation of cell proliferation by ERK and signal-dependent nuclear translocation of ERK is dependent on Tm5NM1-containing actin filaments', Molecular Biology of the Cell, vol. 26, pp. 2475 - 2490, http://dx.doi.org/10.1091/mbc.E14-10-1453

Jalilian I; Heu C; Cheng H; Freittag H; Desouza M; Stehn JR; Bryce NS; Whan RM; Hardeman EC; Fath T, 2015, 'Cell elasticity is regulated by the tropomyosin isoform composition of the actin cytoskeleton', PLoS ONE, vol. 10, http://dx.doi.org/10.1371/journal.pone.0126214

Suchowerska AK; Fath T, 2014, 'Cytoskeletal changes in diseases of the nervous system', Frontiers in Biology, vol. 9, pp. 5 - 17, http://dx.doi.org/10.1007/s11515-014-1290-6

Curthoys NM; Freittag H; Connor A; Desouza M; Brettle M; Poljak A; Hall A; Hardeman E; Schevzov G; Gunning PW, 2014, 'Tropomyosins induce neuritogenesis and determine neurite branching patterns in B35 neuroblastoma cells', Molecular and Cellular Neuroscience, vol. 58, pp. 11 - 21, http://dx.doi.org/10.1016/j.mcn.2013.10.011

Suchowerska A; Chen B; Mueller J; Ittner A; Hardeman E; Ittner L; Janitz M; Gunning P; Fath T, 2013, 'Increased levels of actin filaments containing the tropomyosin Tm5NM1 regulate excitotoxicity in the mouse', MOLECULAR BIOLOGY OF THE CELL, vol. 24, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000209348702020&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Stehn JR; Haass NK; Bonello T; Desouza M; Kottyan G; Treutlein H; Zeng J; Nascimento PRBB; Sequeira VB; Butler TL, 2013, 'A Novel Class of Anticancer Compounds Targets the Actin Cytoskeleton in Tumor Cells', Cancer Research, vol. 73, pp. 5169 - 5182, http://dx.doi.org/10.1158/0008-5472.can-12-4501

Fath T, 2013, 'Tropomodulins and tropomyosins - Organizers of cellular microcompartments', Biomolecular Concepts, vol. 4, pp. 89 - 101, http://dx.doi.org/10.1515/bmc-2012-0037

Schevzov G; Curthoys NM; Gunning PW; Fath T, 2012, 'Functional Diversity of Actin Cytoskeleton in Neurons and its Regulation by Tropomyosin', International Review of Cell and Molecular Biology, vol. 298, pp. 33 - 94, http://dx.doi.org/10.1016/B978-0-12-394309-5.00002-X

Dale RC; Merheb V; Pillai S; Wang D; Cantrill L; Murphy TK; Ben-Pazi H; Varadkar S; Aumann TD; Horne MK, 2012, 'Antibodies to surface dopamine-2 receptor in autoimmune movement and psychiatric disorders', Brain, vol. 135, pp. 3453 - 3468, http://dx.doi.org/10.1093/brain/aws256

Schevzov G; Whittaker SP; Fath T; Lin JJ-C; Gunning PW, 2011, 'Tropomyosin isoforms and reagents', BioArchitecture, vol. 1, pp. 135 - 164, http://dx.doi.org/10.4161/bioa.1.4.17897

Hook J; Lemckert F; Schevzov G; Fath T; Gunning P, 2011, 'Functional identity of the gamma tropomyosin gene: Implications for embryonic development, reproduction and cell viability.', Bioarchitecture, vol. 1, pp. 49 - 59, http://dx.doi.org/10.4161/bioa.1.1.15172

Guven K; Gunning P; Fath T, 2011, 'TPM3 and TPM4 gene products segregate to the postsynaptic region of central nervous system synapses.', Bioarchitecture, vol. 1, pp. 284 - 289, http://dx.doi.org/10.4161/bioa.1.6.19336

Fath T; Fischer RS; Dehmelt L; Halpain S; Fowler VM, 2011, 'Tropomodulins are negative regulators of neurite outgrowth', European Journal of Cell Biology, vol. 90, pp. 291 - 300, http://dx.doi.org/10.1016/j.ejcb.2010.10.014

Hundelt M; Fath T; Selle K; Oesterwind K; Jordan J; Schultz C; Götz J; von Engelhardt J; Monyer H; Lewejohann L, 2011, 'Altered phosphorylation but no neurodegeneration in a mouse model of tau hyperphosphorylation', Neurobiology of Aging, vol. 32, pp. 991 - 1006, http://dx.doi.org/10.1016/j.neurobiolaging.2009.06.007

Fath T; Agnes Chan Y-K; Vrhovski B; Clarke H; Curthoys N; Hook J; Lemckert F; Schevzov G; Tam P; Watson CM, 2010, 'New aspects of tropomyosin-regulated neuritogenesis revealed by the deletion of Tm5NM1 and 2', European Journal of Cell Biology, vol. 89, pp. 489 - 498, http://dx.doi.org/10.1016/j.ejcb.2009.11.028

Fath T; Ke YD; Gunning P; Götz J; Ittner LM, 2009, 'Primary support cultures of hippocampal and substantia nigra neurons', Nature Protocols, vol. 4, pp. 78 - 85, http://dx.doi.org/10.1038/nprot.2008.199

Brandt R; Gergou A; Wacker I; Fath T; Hutter H, 2009, 'A Caenorhabditis elegans model of tau hyperphosphorylation: Induction of developmental defects by transgenic overexpression of Alzheimer's disease-like modified tau', Neurobiology of Aging, vol. 30, pp. 22 - 33, http://dx.doi.org/10.1016/j.neurobiolaging.2007.05.011

Schevzov G; Fath T; Gunning PW, 2009, 'Intracellular structural compartments, disease and tropomyosins', Current Topics in Pharmacology, vol. 13, pp. 1 - 16

Ke YD; Ittner LM; Gunning P; Gotz J; Fath T, 2008, 'P1-142: A new neurotrophic support culture technique for primary neurons', Alzheimer's & Dementia, vol. 4, pp. T248 - T248, http://dx.doi.org/10.1016/j.jalz.2008.05.729

Ittner LM; Ke YD; Fath T; Schonrock N; Gunning P; Gotz J, 2008, 'P2-129: Parkinsonism and memory impairment in tau transgenic mice with axonal transport defects', Alzheimer's & Dementia, vol. 4, pp. T408 - T408, http://dx.doi.org/10.1016/j.jalz.2008.05.1202

Schevzov G; Fath T; Vrhovski B; Vlahovich N; Rajan S; Hook J; Joya JE; Lemckert F; Puttur F; Lin JJ-C, 2008, 'Divergent Regulation of the Sarcomere and the Cytoskeleton', Journal of Biological Chemistry, vol. 283, pp. 275 - 283, http://dx.doi.org/10.1074/jbc.m704392200

Ittner LM; Fath T; Ke YD; Bi M; Van Eersel J; Li KM; Gunning P; Götz J, 2008, 'Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia', Proceedings of the National Academy of Sciences of the United States of America, vol. 105, pp. 15997 - 16002, http://dx.doi.org/10.1073/pnas.0808084105

Götz J; David D; Hoerndli F; Ke YD; Schonrock N; Wiesner A; Fath T; Bokhari L; Lim YA; Deters N, 2008, 'Functional genomics dissects pathomechanisms in tauopathies: Mitosis failure and unfolded protein response', Neurodegenerative Diseases, vol. 5, pp. 179 - 181, http://dx.doi.org/10.1159/000113696

Hundelt M; Selle K; Kosfeld A; Fath T; Schultz C; Götz J; von Engelhardt J; Monyer H; Brandt R, 2007, 'Pseudohyperphosphorylation of tau is sufficient to induce aberrant sprouting and activation of ERK1/2 in transgenic mice', BMC Neuroscience, vol. 8, http://dx.doi.org/10.1186/1471-2202-8-s1-p27

Fath T; Eidenmüller J; Brandt R, 2002, 'Tau-mediated cytotoxicity in a pseudohyperphosphorylation model of Alzheimer's disease', Journal of Neuroscience, vol. 22, pp. 9733 - 9741

Fath T; Eidenmuller J; Wunderlich I; Zobeley S; Hutter H; Brandt R, 2001, 'Simulation of Alzheimer's disease-like tau hyperphosphorylation induces degeneration of neural cells and uncoordinated movements of C-elegans', MOLECULAR BIOLOGY OF THE CELL, vol. 12, pp. 308A - 308A, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000172372501684&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Shahani N; Fath T; Brandt R, 2001, 'MINUS: A negative regulator of microtubule nucleation', MOLECULAR BIOLOGY OF THE CELL, vol. 12, pp. 173A - 173A, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000172372500937&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Eidenmüller J; Fath T; Maas T; Pool M; Sontag E; Brandt R, 2001, 'Phosphorylation-mimicking glutamate clusters in the proline-rich region are sufficient to simulate the functional deficiencies of hyperphosphorylated tau protein.', Biochem J, vol. 357, pp. 759 - 767, https://www.ncbi.nlm.nih.gov/pubmed/11463346

Eidenmüller J; Fath T; Maas T; Pool M; Sontag E; Brandt R, 2001, 'Phosphorylation-mimicking glutamate clusters in the proline-rich region are sufficient to simulate the functional deficiencies of hyperphosphorylated tau protein', Biochemical Journal, vol. 357, pp. 759 - 767, http://dx.doi.org/10.1042/0264-6021:3570759

Fath T; Eidenmüller J; Maas T; Brandt R, 2000, 'Herpes simplex virus-mediated expression of the axonal protein tau in human model neurons (NT2-N cells)', Microscopy Research and Technique, vol. 48, pp. 85 - 96, http://dx.doi.org/10.1002/(SICI)1097-0029(20000115)48:2<85::AID-JEMT4>3.0.CO;2-O

Eidenmuller J; Fath T; Hellwig A; Reed J; Sontag E; Brandt R, 2000, 'Structural and functional implications of tau hyperphosphorylation: Information from phosphorylation-mimicking mutated tau proteins', Biochemistry, vol. 39, pp. 13166 - 13175, http://dx.doi.org/10.1021/bi001290z

Eidenmuller JH; Fath T; Brandt R, 1999, 'Simulation of PHF-like tau phosphorylation in vitro and in cells', MOLECULAR BIOLOGY OF THE CELL, vol. 10, pp. 375A - 375A, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000083673502166&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Maas T; Eidenmuller J; Fath T; Pool M; Brandt R, 1998, 'Protein tau functions as a microtubule plasma membrane linker during neuronal development', MOLECULAR BIOLOGY OF THE CELL, vol. 9, pp. 394A - 394A, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000076906702286&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Conference Papers

Tedla N; An H; Fath T; Lord M; Bryant K, 2017, 'Leukocyte immunoglobulin-like receptor A3 (LILRA3) displays anti-inflammatory and neuro-regenerative functions through interaction with multiple ligands', in JOURNAL OF IMMUNOLOGY, AMER ASSOC IMMUNOLOGISTS, Washington, DC, presented at Annual Meeting of the American-Association-of-Immunologists (AAI), Washington, DC, 12 - 16 May 2017, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000407757000578&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Stehn JR; Haass NK; Bonello T; Desouza M; Kottyan G; Treutlein H; Zeng J; Nascimento PR; Butler T; Allanson M, 2012, 'Developing chemotherapeutics which selectively disable the actin cytoskeleton of tumor cells', in EXPERIMENTAL DERMATOLOGY, WILEY-BLACKWELL, Marburg, GERMANY, pp. e43 - e43, presented at 39th Annual Meeting of the Arbeitsgemeinschaft-Dermatologische-Forschung (ADF), Marburg, GERMANY, 01 - 03 March 2012, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000300931700252&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Curthoys N; Freittag H; Connor A; Desouza M; Hardeman E; Gunning P; Schevzov G; Fath T, 2011, 'Tropomyosins induce neurite formation in B35 neuroblastoma cells and control neurite branching', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Denver, CO, presented at Annual Meeting of the American-Society-for-Cell-Biology (ASCB), Denver, CO, 03 - 07 December 2011, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000305505503094&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Fath T; Fowler VM, 2004, 'Tropomodulin and actin pointed-end dynamics in neuronal model systems', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Washington, DC, pp. 25A - 25A, presented at Annual Meeting of the American-Society-for-Cell-Biology, Washington, DC, 04 - 08 December 2004, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000224648800138&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Conference Posters

Suchowerska A; Chen B; Mueller J; Ittner A; Hardeman E; Ittner L; Janitz M; Gunning P; Fath T, 2013, 'Increased levels of actin filaments containing the tropomyosin Tm5NM1 regulate excitotoxicity in the mouse', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Vol. 24, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000209348705376&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Conference Presentations

Jalilian I; Schevzov G; Fath T; Heu C; Bischof L; Vindin H; Stehn JR; Tate MK; Hardeman EC; Gunning PW, 2014, 'Determining the impact of the actin cytoskeleton on the mechanical properties of cells.', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Philadelphia, PA, Vol. 25, presented at ASCB/IFCB Meeting, Philadelphia, PA, 06 - 10 December 2014, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000352094100060&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Conference Abstracts

Fath T; Brettle M; Janitz M; Gunning P, 2015, 'Manipulation of the actin cytoskeleton promotes neurite outgrowth on inhibitory substrates', in JOURNAL OF NEUROCHEMISTRY, WILEY-BLACKWELL, Cairns, AUSTRALIA, Vol. 134, pp. 311 - 311, presented at 25th Biennial Meeting of the International-Society-for-Neurochemistry Jointly with the 13th Meeting of the Asian-Pacific-Society-for-Neurochemistry in Conjunction with the 35th Meeting of the Australa, Cairns, AUSTRALIA, 23 - 27 August 2015, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000360206300790&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Brettle M; Suchowerska A; Chua SW; Ittner L; Fath T, 2015, 'Functional analysis of amyotrophic lateral sclerosis-associated mutations of profilin 1 in primary mouse neurons', in JOURNAL OF NEUROCHEMISTRY, WILEY-BLACKWELL, Cairns, AUSTRALIA, Vol. 134, pp. 195 - 195, presented at 25th Biennial Meeting of the International-Society-for-Neurochemistry Jointly with the 13th Meeting of the Asian-Pacific-Society-for-Neurochemistry in Conjunction with the 35th Meeting of the Australa, Cairns, AUSTRALIA, 23 - 27 August 2015, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000360206300470&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

Nguyen HL; Fath T; Jones N, 2015, 'The effects of hypoxic postconditioning in a rat model of endothelin-1 induced middle cerebral ischemia', in JOURNAL OF NEUROCHEMISTRY, WILEY-BLACKWELL, Cairns, AUSTRALIA, Vol. 134, pp. 294 - 295, presented at 25th Biennial Meeting of the International-Society-for-Neurochemistry Jointly with the 13th Meeting of the Asian-Pacific-Society-for-Neurochemistry in Conjunction with the 35th Meeting of the Australa, Cairns, AUSTRALIA, 23 - 27 August 2015, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000360206300744&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a

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