Associate Professor Andrew Moorhouse
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Publications related to this Person
Book Chapters
Moorhouse AJ, 2022, 'Molecular Principles, Components, Technology, and Concepts: Membranes – Membrane Potential: Concepts', in Reference Module in Life Sciences, Elsevier, http://dx.doi.org/10.1016/b978-0-12-821618-7.00200-5
Wake H; Horiuchi H; Kato D; Moorhouse AJ; Nabekura J, 2019, 'Physiological Implications of Microglia–Synapse Interactions', in Methods in Molecular Biology, United States, pp. 69 - 80, http://dx.doi.org/10.1007/978-1-4939-9658-2_6
Kato D; Ikegami A; Horiuchi H; Moorhouse AJ; Nabekura J; Wake H, 2019, 'In Vivo Two-Photon Imaging of Microglial Synapse Contacts', in Methods in Molecular Biology, United States, pp. 281 - 286, http://dx.doi.org/10.1007/978-1-4939-9658-2_20
Moorhouse AJ, 2016, 'Membrane Potential: Concepts', in Encyclopedia of Cell Biology, pp. 218 - 236, http://dx.doi.org/10.1016/B978-0-12-394447-4.10027-6
Moorhouse AJ; Lewis TM; Barry PH, 2015, 'Analyzing Ion Permeation in Channels and Pumps Using Patch-Clamp Recording', in Clarke RJ; Khalid MAA (ed.), Pumps, Channels and Transporters Methods of Functional Analysis, John Wiley & Sons, Hoboken, New Jersey, pp. 51 - 88, http://dx.doi.org/10.1002/9781119085126.ch3
Ishibashi H; Moorhouse AJ; Nabekura J, 2012, 'Perforated Whole-Cell Patch-Clamp Technique: A User’s Guide', in Okada Y (ed.), Patch Clamp Techniques: From Beginning to Advanced Protocols, edn. 1st, Springer, Tokyo, pp. 71 - 83, http://dx.doi.org/10.1007/978-4-431-53993-3
Ishibashi H; Moorhouse AJ; Nabekura J, 2012, 'Perforated Whole-Cell Patch-Clamp Technique: A User’s Guide', in Springer Protocols Handbooks, Springer Japan, pp. 71 - 83, http://dx.doi.org/10.1007/978-4-431-53993-3_4
Moorhouse AJ; Nabekura J, 2011, 'Cellular Mechanisms of neuronal Homeostasis and its Modulation by Neuronal Injury', in Woodin MA; Maffei A (ed.), Inhibitory Synaptic Plasticity, Springer, New York, pp. 123 - 134, http://dx.doi.org/10.1007/978-1-4419-6978-1_9
Barry PH; Qu W; Moorhouse AJ, 2008, 'Biophysics of CNG Ion Channels', in Martinac B (ed.), Sensing with Ion Channels, edn. Original, Springer, Berlin Heidelberg, pp. 175 - 200
Journal articles
Takeda I; Yoshihara K; Cheung DL; Kobayashi T; Agetsuma M; Tsuda M; Eto K; Koizumi S; Wake H; Moorhouse AJ; Nabekura J, 2022, 'Controlled activation of cortical astrocytes modulates neuropathic pain-like behaviour', Nature Communications, vol. 13, pp. 4100, http://dx.doi.org/10.1038/s41467-022-31773-8
Cheung DL; Cooke MJ; Goulton CS; Chaichim C; Cheung LF; Khoshaba A; Nabekura J; Moorhouse AJ, 2022, 'Global transgenic upregulation of KCC2 confers enhanced diazepam efficacy in treating sustained seizures', Epilepsia, vol. 63, pp. e15 - e22, http://dx.doi.org/10.1111/epi.17097
Okada T; Kato D; Nomura Y; Obata N; Quan X; Morinaga A; Yano H; Guo Z; Aoyama Y; Tachibana Y; Moorhouse AJ; Matoba O; Takiguchi T; Mizobuchi S; Wake H, 2021, 'Pain induces stable, active microcircuits in the somatosensory cortex that provide a therapeutic target', Science Advances, vol. 7, http://dx.doi.org/10.1126/sciadv.abd8261
Ozaki K; Kato D; Ikegami A; Hashimoto A; Sugio S; Guo Z; Shibushita M; Tatematsu T; Haruwaka K; Moorhouse AJ; Yamada H; Wake H, 2020, 'Maternal immune activation induces sustained changes in fetal microglia motility', Scientific Reports, vol. 10, http://dx.doi.org/10.1038/s41598-020-78294-2
Karunanithi S; Lin YQ; Lorenzo Odierna G; Menon H; Gonzalez JM; Gregory Neely G; Noakes PG; Lavidis NA; Moorhouse AJ; van Swinderen B, 2020, 'Activity-dependent global downscaling of evoked neurotransmitter release across glutamatergic inputs in Drosophila', Journal of Neuroscience, vol. 40, pp. 8025 - 8041, http://dx.doi.org/10.1523/JNEUROSCI.0349-20.2020
Kato D; Wake H; Lee PR; Tachibana Y; Ono R; Sugio S; Tsuji Y; Tanaka YH; Tanaka YR; Masamizu Y; Hira R; Moorhouse AJ; Tamamaki N; Ikenaka K; Matsukawa N; Fields RD; Nabekura J; Matsuzaki M, 2020, 'Motor learning requires myelination to reduce asynchrony and spontaneity in neural activity', GLIA, vol. 68, pp. 193 - 210, http://dx.doi.org/10.1002/glia.23713
Haruwaka K; Ikegami A; Tachibana Y; Ohno N; Konishi H; Hashimoto A; Matsumoto M; Kato D; Ono R; Kiyama H; Moorhouse AJ; Nabekura J; Wake H, 2019, 'Dual microglia effects on blood brain barrier permeability induced by systemic inflammation', Nature Communications, vol. 10, http://dx.doi.org/10.1038/s41467-019-13812-z
Nakamura K; Moorhouse AJ; Cheung DL; Eto K; Takeda I; Rozenbroek PW; Nabekura J, 2019, 'Overexpression of neuronal K + –Cl − co-transporter enhances dendritic spine plasticity and motor learning', Journal of Physiological Sciences, vol. 69, pp. 453 - 463, http://dx.doi.org/10.1007/s12576-018-00654-5
Moorhouse AJ; Power JM, 2019, 'Making light work of fine-tuning channelrhodopsins', Journal of Biological Chemistry, vol. 294, pp. 3822 - 3823, http://dx.doi.org/10.1074/jbc.H119.007749
Gorlamandala N; Parmar J; Craig AJ; Power JM; Moorhouse AJ; Krishnan AV; Housley GD, 2018, 'Focal Ischaemic Infarcts Expand Faster in Cerebellar Cortex than Cerebral Cortex in a Mouse Photothrombotic Stroke Model', Translational Stroke Research, vol. 9, pp. 643 - 653, http://dx.doi.org/10.1007/s12975-018-0615-1
Akiyoshi R; Wake H; Kato D; Horiuchi H; Ono R; Ikegami A; Haruwaka K; Omori T; Tachibana Y; Moorhouse AJ; Nabekura J, 2018, 'Microglia enhance synapse activity to promote local network synchronization', eNeuro, vol. 5, http://dx.doi.org/10.1523/ENEURO.0088-18.2018
Goulton CS; Watanabe M; Cheung DL; Wang KW; Oba T; Khoshaba A; Lai D; Inada H; Eto K; Nakamura K; Power JM; Lewis TM; Housley GD; Wake H; Nabekura J; Moorhouse AJ, 2018, 'Conditional Upregulation of KCC2 selectively enhances neuronal inhibition during seizures', , http://dx.doi.org/10.1101/253831
Ishikawa T; Eto K; Kim SK; Wake H; Takeda I; Horiuchi H; Moorhouse AJ; Ishibashi H; Nabekura J, 2018, 'Cortical astrocytes prime the induction of spine plasticity and mirror image pain', Pain, vol. 159, pp. 1592 - 1606, http://dx.doi.org/10.1097/j.pain.0000000000001248
Nakahata Y; Eto K; Murakoshi H; Watanabe M; Kuriu T; Hirata H; Moorhouse AJ; Ishibashi H; Nabekura J, 2017, 'Activation-dependent rapid postsynaptic clustering of glycine receptors in mature spinal cord neurons', eNeuro, vol. 4, http://dx.doi.org/10.1523/ENEURO.0194-16.2017
Miyamoto A; Wake H; Ishikawa AW; Eto K; Shibata K; Murakoshi H; Koizumi S; Moorhouse AJ; Yoshimura Y; Nabekura J, 2016, 'Microglia contact induces synapse formation in developing somatosensory cortex', Nature Communications, vol. 7, http://dx.doi.org/10.1038/ncomms12540
Kim SK; Hayashi H; Ishikawa T; Shibata K; Shigetomi E; Shinozaki Y; Inada H; Roh SE; Kim SJ; Lee G; Bae H; Moorhouse AJ; Mikoshiba K; Fukazawa Y; Koizumi S; Nabekura J, 2016, 'Cortical astrocytes rewire somatosensory cortical circuits for peripheral neuropathic pain', Journal of Clinical Investigation, vol. 126, pp. 1983 - 1997, http://dx.doi.org/10.1172/JCI82859
Kato G; Inada H; Wake H; Akiyoshi R; Miyamoto A; Eto K; Ishikawa T; Moorhouse AJ; Strassman AM; Nabekura J, 2016, 'Microglial contact prevents excess depolarization and rescues neurons from excitotoxicity', eNeuro, vol. 3, pp. 9133 - 9144, http://dx.doi.org/10.1523/ENEURO.0004-16.2016
Alexander SPH; Benson HE; Faccenda E; Pawson AJ; Sharman JL; McGrath JC; Catterall WA; Spedding M; Peters JA; Harmar AJ, 2013, 'THE CONCISE GUIDE TO PHARMACOLOGY 2013/14: OVERVIEW', BRITISH JOURNAL OF PHARMACOLOGY, vol. 170, pp. 1449 - 1458, http://dx.doi.org/10.1111/bph.12444
Barry PH; Lewis TM; Moorhouse AJ, 2013, 'An optimised 3 M KCl salt-bridge technique used to measure and validate theoretical liquid junction potential values in patch-clamping and electrophysiology', European Biophysics Journal, vol. 42, pp. 631 - 646, http://dx.doi.org/10.1007/s00249-013-0911-3
Miyamoto A; Wake H; Moorhouse AJ; Nabekura J, 2013, 'Microglia and synapse interactions: Fine tuning neural circuits and candidate molecules', Frontiers in Cellular Neuroscience, vol. 7, http://dx.doi.org/10.3389/fncel.2013.00070
Wake H; Moorhouse AJ; Miyamoto A; Nabekura J, 2013, 'Microglia: Actively surveying and shaping neuronal circuit structure and function', Trends in Neurosciences, vol. 36, pp. 209 - 217, http://dx.doi.org/10.1016/j.tins.2012.11.007
Kim YS; Wong AC; Power J; Tadros SF; Klugmann M; Moorhouse AJ; Bertrand PP; Housley GD, 2012, 'Alternative Splicing of the TRPC3 Ion Channel Calmodulin/ IP3 Receptor-Binding Domain in the Hindbrain Enhances Cation Flux', The Journal of Neuroscience, vol. 32, pp. 11414 - 11423, http://dx.doi.org/10.1523/JNEUROSCI.6446-11.2012
Eto K; Ishibashi H; Yoshimura T; Watanabe M; Miyamoto A; Ikenaka K; Moorhouse AJ; Nabekura J, 2012, 'Enhanced GABAergic activity in the mouse primary somatosensory cortex is insufficient to alleviate chronic pain behavior with reduced expression of neuronal potassium-chloride cotransporter', Journal of Neuroscience, vol. 32, pp. 16552 - 16559, http://dx.doi.org/10.1523/JNEUROSCI.2104-12.2012
Wake H; Moorhouse AJ; Nabekura J, 2012, 'Functions of microglia in the central nervous system-beyond the immune response', Neuron Glia Biology, vol. 7, pp. 47 - 53, http://dx.doi.org/10.1017/S1740925X12000063
Nakahata Y; Miyamoto A; Watanabe M; Moorhouse AJ; Nabekura J; Ishibashi H, 2010, 'Depolarizing shift in the GABA-induced current reversal potential by lidocaine hydrochloride', Brain Research, vol. 1345, pp. 19 - 27, http://dx.doi.org/10.1016/j.brainres.2010.05.052
Sugiharto S; Carland JE; Lewis TM; Moorhouse AJ; Barry PH, 2010, 'External divalent cations increase anion-cation permeability ratio in glycine receptor channels', Pflugers Archiv - European Journal of Physiology, vol. 460, pp. 131 - 152, http://dx.doi.org/10.1007/s00424-010-0792-6
Barry PH; Sugiharto S; Lewis TM; Moorhouse AJ, 2010, 'Further analysis of counterion permeation through anion-selective glycine receptor channels.', Channels, vol. 4, pp. 142 - 149, http://www.landesbioscience.com/journals/channels/article/11020
Watanabe M; Wake H; Moorhouse AJ; Nabekura J, 2009, 'Clustering of Neuronal K+-Cl- Cotransporters in Lipid Raftsby Tyrosine Phosphorylation', The Journal of Biological Chemistry, vol. 284, pp. 27980 - 27988, http://dx.doi.org/10.1074/jbc.M109.043620
Carland JE; cooper MA; Sugiharto S; Jeong H; Lewis TM; Barry PH; Peters JA; Lambert J; Moorhouse AJ, 2009, 'Characterization of the effects of charged residues in the intracellular loop on ion permeation in α1 glycine receptor channels', The Journal of Biological Chemistry, vol. 284, pp. 2023 - 2030, http://dx.doi.org/10.1074/jbc.M806618200
Wake H; Moorhouse AJ; Jinno S; Kohsaka S; Nabekura J, 2009, 'Resting microglia directly monitor the functional state of synapses in vivo and determine the fate of ischemic terminals', Journal of Neuroscience, vol. 29, pp. 3974 - 3980, http://dx.doi.org/10.1523/JNEUROSCI.4363-08.2009
Park E; Choi I; Cho J; Nakamura M; Lee J; Lee M; Choi B; Moorhouse AJ; Jang I, 2008, 'Zinc modulation of glycine receptors in acutely isolated rat CA3 neurons', Life Sciences, vol. 83, pp. 149 - 154, http://dx.doi.org/10.1016/j.lfs.2008.04.024
Sugiharto S; Lewis TM; Moorhouse AJ; Schofield PR; Barry PH, 2008, 'Anion-cation permeability correlates with hydrated counterion size in glycine receptor channels', Biophysical Journal, vol. 95, pp. 4698 - 4715, http://dx.doi.org/10.1529/biophysj.107.125690
Wake H; Watanabe M; Moorhouse AJ; Kanematsu T; Horibe S; Matsukawa N; Asai K; Ojika K; Hirata M; Nabekura J, 2007, 'Early changes in KCC2 phosphorylation in response to neuronal stress result in functional downregulation', Journal of Neuroscience, vol. 27, pp. 1642 - 1650, http://dx.doi.org/10.1523/JNEUROSCI.3104-06.2007
Qu W; Moorhouse AJ; Chandra M; Pierce KD; Lewis TM; Barry PH, 2006, 'A single P-loop glutamate point mutation to either lysine or arginine switches the cation-anion selectivity of the CNGA2 channel', Journal of General Physiology, vol. 127, pp. 375 - 389, http://dx.doi.org/10.1085/jgp.200509378
Qu W; Moorhouse AJ; Lewis TM; Pierce KD; Barry PH, 2005, 'Mutation of the pore glutamate affects both cytoplasmic and external dequalinium block in the rat olfactory CNGA2 channel', European Biophysics Journal with Biophysics Letters, vol. 34, pp. 442 - 453, http://dx.doi.org/10.1007/s00249-005-0479-7
Moorhouse AJ; Li S; Vickery RM; Hill MA; Morley JW, 2004, 'A patch-clamp investigation of membrane currents in a novel mammalian retinal ganglion cell line', Brain Research, vol. 1003, pp. 205 - 208, http://dx.doi.org/10.1016/j.brainres.2004.01.027
Keramidas A; Moorhouse AJ; Schofield PR; Barry PH, 2004, 'Ligand-gated ion channels: mechanisms underlying ion selectivity', Progress in Biophysics and Molecular Biology, vol. 86, pp. 161 - 204, http://dx.doi.org/10.1016/j.pbiomolbio.2003.09.002
Carland JE; Moorhouse AJ; Barry PH; Johnston G; Chebib M, 2004, 'Charged residues at the 2 ` position of human GABA(c) rho 1 receptorsinvert ion selectivity and influence open state probability', The Journal of Biological Chemistry, vol. 279, pp. 54153 - 54160, http://dx.doi.org/10.1074/jbc.M410625200
Katsurabayashi S; Kubota H; Moorhouse AJ; Akaike N, 2004, 'Differential modulation of evoked and spontaneous glycine release fromrat spinal cord glycinergic terminals by the cyclic AMP/protein kinaseA transduction cascade', Journal of Neurochemistry, vol. 91, pp. 657 - 666, http://dx.doi.org/10.1111/j.1471-4159.2004.02741.x
Kubota H; Katsurabayashi S; Moorhouse AJ; Murakami N; Koga H; Akaike N, 2003, 'GABA
Lee DJ; Keramidas A; Moorhouse AJ; Schofield PR; Barry PH, 2003, 'The contribution of P250 (P-2`D) to ion selectivity and pore diameter in the human glycine receptor.', Neuroscience Letters, vol. 351, pp. 196 - 200, http://dx.doi.org/10.1016/j.neulet.2003.08.005
Jeong H; Jan I; Moorhouse AJ; Akaike N, 2003, 'Activation of presynaptic glycine receptors facilitate glycine release from presynaptic terminals synapsing onto rat spinal sacral dorsal commissural nucleus nerons', The Journal of Physiology, vol. 550, pp. 373 - 383, http://dx.doi.org/10.1113/jphysiol.2003.041053
Akaike N; Moorhouse AJ, 2003, 'Techniques: Applications of the Nerve - bouton preparation in Neuropharmacology', Trends in Pharmacological Sciences, vol. 24, pp. 44 - 47, http://dx.doi.org/10.1016/S0165-6147(02)00010-X
Kubota H; Katsurabayashi S; Moorhouse AJ; Murakami N; Koga H; Akaike N, 2003, 'GABAB receptor transduction mechanisms, and cross-talk between protein kinases A and C, in GABAergic terminals synapsing onto neurons of the rat nucleus basalis of Meynert', The Journal of Physiology, vol. 551, pp. 263 - 276, http://dx.doi.org/10.1113/jphysiol.2003.046524
Keramidas A; Moorhouse AJ; Pierce K; Schofield PR; Barry PH, 2002, 'Cation-selective mutations in the M2 domain of the inhibitory glycine receptor channel reveal determinants of ion charge selectivity', Journal of General Physiology, vol. 119, pp. 393 - 410, http://dx.doi.org/10.1085/jgp.20028552
Moorhouse AJ; Keramidas A; Zaikine A; Zaykin A; Schofield PR; Barry PH, 2002, 'Single channel analysis of conductance and rectification in cation-selective, mutant glycine receptor channels', Journal of General Physiology, vol. 119, pp. 411 - 425, http://dx.doi.org/10.1085/jgp.20028553
Kaur R; Zhu XO; Moorhouse AJ; Barry PH, 2001, 'Ip
Qu W; Moorhouse AJ; Cunningham AM; Barry PH, 2001, 'Anomalous Mole-Fraction Effects in Recombinat & Native Cyclic Nucleotide-Gated Channels in Rat Olfactory Receptor Neurons', Proceedings of the Royal Society of London Series B - Biological Sciences, vol. 268, pp. 1395 - 1403, http://dx.doi.org/10.1098/rspb.2001.1663
Kaur R; Zhu X; Moorhouse AJ; Barry PH, 2001, 'IP3-Gated Channels and their Occurrence Relative to CNG Channels in the Soma and Dendritic Knob of Rat Olfactory Receptor Neurons', Journal of Membrane Biology, vol. 181, pp. 91 - 105, https://www.ncbi.nlm.nih.gov/pubmed/11420596
Keramidas A; Moorhouse AJ; French CD; Schofield PR; Barry PH, 2000, 'M2 pore mutations convert the glycine receptor channel from being anion- to cation-selective', Biophysical Journal, pp. 247 - 259
Qu W; Zhu X; Moorhouse AJ; Bieri S; Cunningham AM, 2000, 'Ion permeation and selectivity of wild-type recombinant rat (CNG (rOCNC1) chanels expressed in HEK293 cells', Journal of Membrane Biology, vol. 178, pp. 137 - 150, http://dx.doi.org/10.1007/s002320010021
Keramidas A; Moorhouse AJ; French C; Schofield PR; Barry PH, 2000, 'M2 pore mutations convert the glycine receptor channel from being anion to cation selective', Biophysical Journal, vol. 78, pp. 247 - 259, http://dx.doi.org/10.1016/S0006-3495(00)76287-4
Qu W; Moorhouse AJ; Rajendra S; Barry PH, 2000, 'Very negative potential for half-inactivation of and effects of anions on voltage-dependent sodium currents in acutely isolated rat olfactory receptor neurons', Journal of Membrane Biology, vol. 175, pp. 123 - 138, http://dx.doi.org/10.1007/s002320001061
Barry PH; Schofield PR; Moorhouse AJ, 1999, 'Glycine receptors: What gets in and why?', Clinical and Experimental Pharmacology and Physiology, pp. 935 - 936
Barry PH; Schofield PR; Moorhouse AJ, 1999, 'Glycine receptors: What gets in and why', Clinical and Experimental Pharmacology and Physiology, vol. 26, pp. 935 - 936, http://dx.doi.org/10.1046/j.1440-1681.1999.03149.x
Moorhouse AJ; Jacques P; Barry PH; Schofield PR, 1999, 'The startle disease mutation Q266H, in the second transmembrane domain of the human glycine receptor, impairs channel gating', Molecular Pharmacology, vol. 55, pp. 386 - 395, http://dx.doi.org/10.1124/mol.55.2.386
Keramidas A; Kuhlmann L; Moorhouse AJ; Barry PH, 1999, 'Measurement of the limiting equivalent conductivities and mobilities of the most prevalent ionic species of EGTA (EGTA2-and EGTA3-) for use in electrophysiological experiments', Journal of Neuroscience Methods, vol. 89, pp. 41 - 47, http://dx.doi.org/10.1016/S0165-0270(99)00036-9
Smith PR; Proks P; Moorhouse AJ, 1999, 'Direct effects of tolutamide on mitochondrial function, intracellular Ca2+ and exocytosis in pancreatic beta-cells', Pflugers Archiv - European Journal of Physiology, vol. 437, pp. 577 - 588, http://dx.doi.org/10.1007/s004240050820
Proks P; Moorhouse A; Smith PA; Ashcroft FM, 1996, 'Protein kinase C does not influence the tolbutamide sensitivity of K-ATP currents', DIABETOLOGIA, vol. 39, pp. 105 - 105, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1996VA49300106&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Ämmälä C; Moorhouse A; Gribble F; Ashfield R; Proks P; Smith PA; Sakura H; Coles B; Ashcroft SJH; Ashcroft FM, 1996, 'Promiscuous coupling between the sulphonylurea receptor and inwardly rectifying potassium channels', Nature, vol. 379, pp. 545 - 548, http://dx.doi.org/10.1038/379545a0
Tucker SJ; Pessia M; Moorhouse AJ; Gribble F; Ashcroft FM; Maylie J; Adelman JP, 1996, 'Heteromeric channel formation and Ca2+-free media reduce the toxic effect of the weaver K 3.2 allele', FEBS Letters, vol. 390, pp. 253 - 257, http://dx.doi.org/10.1016/0014-5793(96)00635-7
Ammala C; Moorhouse AJ; Ashcroft FM, 1996, 'The sulphonylurea receptor confers diazoxide sensitivity on the inwardly rectifying Kir6.1 expressed in human embroyonic kidney cells', The Journal of Physiology, vol. 494, pp. 709 - 714, http://dx.doi.org/10.1113/jphysiol.1996.sp021526
MOORHOUSE AJ; SPENCE I, 1995, 'SYNAPTIC TRANSMISSION, HYPOXIA AND ADENOSINE IN THE ISOLATED NEONATAL RAT SPINAL-CORD', JOURNAL OF PHYSIOLOGY-LONDON, vol. 489P, pp. P23 - P23, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1995TH85400029&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Takeda I; Yoshihara K; Cheung D; Agetsuma M; Tsuda M; Eto K; Moorhouse A; Nabekura J, 'Controlled activation of cortical astrocytes can reverse neuropathic chronic pain', , http://dx.doi.org/10.21203/rs.3.rs-150434/v1
Conference Papers
Kim YS; Moorhouse AJ; Bertrand PP; Klugmann M; Housley GD, 2013, 'Alternative splicing of Canonical Transient Receptor Potential type 3 (TRPC3) ion channel expression in the human brain', in Journal of Neurological Sciences vol 333, Elsevier, Vienna, Austria, pp. e654, presented at World Congress of Neurology, Vienna, Austria, 21 September 2013 - 26 September 2013, http://www.journals.elsevier.com/journal-of-the-neurological-sciences/
Moorhouse AJ; Sugiharto S; Carland JE; Lewis TM; Barry PH, 2012, 'Anion selectivity and counter-ion cation permeation in glycine receptor channels.', in FASEB JOURNAL Volume: 26 Published: APR 2012, American Physiology Society, Abs#, 901.2., San Diego, CA, presented at Experimental Biology Meeting, San Diego, CA, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000310711303579&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
Barry PH; Lewis TM; Moorhouse AJ, 2011, 'An improved method, with theoretical analyses, for the simple experimental measurement of liquid junction potentials', Wollongong, presented at BioPhysChem 2011, a joint meeting of the RACI Physical Chemistry Division and the Australian Society for Biophysics,, Wollongong
Wake H; Moorhouse AJ; Jinno S; Kohsaka S; Nabekura J, 2008, 'Resting microglia directly monitor synapses in vivo and determine the fate of ischemic terminals', in Neuroscience Research, Elsevier Sci Ireland Ltd, Clare, Ireland, pp. S152 - S152, presented at Neuroscience Research, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000261548101055&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
Conference Posters
Barry PH; Lewis TM; Moorhouse AJ, 2013, 'Experimental and theoretical validation of calculated liquid junction potentials in monovalent ion solutions and effects of divalent ions', in Experimental and theoretical validation of calculated liquid junction potentials in monovalent ion solutions and effects of divalent ions, 37th Annual Meeting of the Australian Society for Biophysics, RMIT, Melbourne, presented at 37th Annual Meeting of the Australian Society for Biophysics, RMIT, Melbourne, 24 November 2013 - 27 November 2013
Khoshaba ; Power J; Moorhouse AJ, 2013, 'Quantifying KCC2 activity in isolated hippocampal neurons using fluorescent imaging. Poster presentation', in Quantifying KCC2 activity in isolated hippocampal neurons using fluorescent imaging. Poster presentation, Gage Conference on Ion Channels and Transporters, Canberra, presented at Gage Conference on Ion Channels and Transporters, Canberra, 17 April 2013 - 20 April 2013
Moorhouse A; Carland JE; Cooper MA; Sugiharto S; Jeong H-J; Lewis TM; Barry PH; Peters JA; Lambert JJ, 2009, 'Molecular determinants of ion permeation in glycine receptor-channels: characterising charged residues in the intracellular M3-M4 loop', in JOURNAL OF PHYSIOLOGICAL SCIENCES, SPRINGER TOKYO, Kyoto, Japan, Vol. 59, pp. 393 - 393, presented at 36th International Congress of Physiological Societies, Kyoto, Japan, 27 July 2009 - 01 August 2009, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000271023102614&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
Barry PH; Sugiharto S; Carland JE; Lewis TM; Moorhouse AJ, 2009, 'Do divalent cations increase the anion-cation permeability in glycine receptor channels, even with initial offset and activity corrections?', in Journal of Physiological Sciences, Springer Japan KK, Japan, Vol. 59, pp. 393 - 393, presented at 36th International Congress of Physiological Sciences, Kyoto, Japan, 27 July 2009 - 01 August 2009, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000271023102616&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
Conference Presentations
Cederholm J; Goulton C; Vickery R; Moorhouse A, 2020, 'Online peer assessment: Challenges, triumphs and lessons learnt during COVID-19', UNSW Sydney, presented at UNSW Medicine & Health Education Forum, UNSW Sydney, 04 December 2020
Cederholm J; Goulton C; Vickery R; Moorhouse A, 2020, 'Our challenges and triumphs with online peer assessment in a fully remote course.', presented at Australian Physiological Society Education Forum, 25 November 2020
Cederholm J; Goulton C; Vickery R; Moorhouse A, 2020, 'Student Peer Assessment Using Moodle Workshop: Challenges in a COVID-19 world.', presented at UNSW Learning & Teaching Forum, 19 November 2020 - 20 November 2020
Moorhouse AJ, 2013, 'Upregulating KCC2 enhances neuronal inhibition. Oral presentation, Gage Conference on Ion Channels and Transporters', in Upregulating KCC2 enhances neuronal inhibition. Oral presentation, Gage Conference on Ion Channels and Transporters, Canberra,, Canberra,, 17 April 2013 - 20 April 2013
Barry PH; Lewis TM; Moorhouse AJ, 2011, 'An improved method, with theoretical analysis, for the simple experimental measurement of liquid junction potentials', in An improved method, with theoretical analysis, for the simple experimental measurement of liquid junction potentials, Joint ASB-BioPhysChem 2011 Conference, University of Wollongong, NSW, Australia, presented at Joint ASB-BioPhysChem 2011 Conference, University of Wollongong, NSW, Australia, 03 December 2011 - 06 December 2011
Barry PH; Sugiharto S; Carland JE; Moorhouse AJ; Lewis TM, 2009, 'Permeability measurements in anion channels: effects of divalent cations, liquid junction potentials and offsets', in Permeability measurements in anion channels: effects of divalent cations, liquid junction potentials and offsets, 33rd Annual Meeting of the Australian Society for Biophysics, Ballarat, NSW, Australia, presented at 33rd Annual Meeting of the Australian Society for Biophysics, Ballarat, NSW, Australia, 29 November 2009
Barry PH; Sugiharto S; Carland JE; Lewis TM; Moorhouse AJ, 2009, 'The lack of certain activity corrections and initial offset corrections can produce erroneous anion-cation permeability ratios in GlyR channels', in The lack of certain activity corrections and initial offset corrections can produce erroneous anion-cation permeability ratios in GlyR channels, Curtin Conference, RMIT, Melbourne, VIC, presented at Curtin Conference, RMIT, Melbourne, VIC, 15 April 2009 - 17 April 2009
Carland JE; Cooper MA; Sugiharto S; Jeong H; Lewis TM; Barry PH; Lambert J; Peters JA; Moorhouse AJ, 2008, 'Charged residues in the intracellular loop affect the conductance of glycine α1 receptors', in Charged residues in the intracellular loop affect the conductance of glycine α1 receptors, Ligand Gated Ion Channels: 18th Neuropharmacology Conference, Washington DC, USA, presented at Ligand Gated Ion Channels: 18th Neuropharmacology Conference, Washington DC, USA, 12 November 2008 - 14 November 2008
Carland JE; Cooper MA; Sugiharto S; Jeong H; Lewis TM; Barry PH; Lambert J; Peters JA; Moorhouse AJ, 2008, 'The role of intracellular portals in glycine receptor ion permeation', in The role of intracellular portals in glycine receptor ion permeation, 32nd Annual Meeting of the Australian Society for Biophysics, Australian National University, Canberra, Australia, presented at 32nd Annual Meeting of the Australian Society for Biophysics, Australian National University, Canberra, Australia, 28 September 2008 - 01 October 2008
Sugiharto S; Moorhouse AJ; Lewis TM; Schofield PR; Barry PH, 2007, 'The anion-cation permeability ratio in glycine receptor channels of different pore size is influenced by both counter-ions and divalent ions', in The anion-cation permeability ratio in glycine receptor channels of different pore size is influenced by both counter-ions and divalent ions, 7th International Brain Research Organization World Congress of Neuroscience, Melbourne, Australia, presented at 7th International Brain Research Organization World Congress of Neuroscience, Melbourne, Australia
Zhu XO; Qu W; Moorhouse AJ; Cunningham AM; Barry PH, 2001, 'Spermine block in alpha homomeric recombinant olfactory CNG channels', in BIOPHYSICAL JOURNAL, BIOPHYSICAL SOCIETY, Vol. 80, pp. 633A - 633A, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000166692202880&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Conference Abstracts
Cheung D; Goulton C; Cooke M; Cowan A; Klugmann M; Moorhouse A, 2015, 'Effects of prolonged diazepam administration on hippocampal EEG and histology in a mouse model of temporal lobe epilepsy', in JOURNAL OF NEUROCHEMISTRY, WILEY-BLACKWELL, Cairns, AUSTRALIA, Vol. 134, pp. 138 - 138, presented at 25th Biennial Meeting of the International-Society-for-Neurochemistry Jointly with the 13th Meeting of the Asian-Pacific-Society-for-Neurochemistry in Conjunction with the 35th Meeting of the Australasian-Neuroscience-Society, Cairns, AUSTRALIA, 23 August 2015 - 27 August 2015, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000360206300315&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Khoshaba A; Power J; Inada H; Nabekura J; Moorhouse A, 2015, 'Measuring KCC2 function in brain slices using BCECF imaging', in JOURNAL OF NEUROCHEMISTRY, WILEY-BLACKWELL, Cairns, AUSTRALIA, Vol. 134, pp. 159 - 159, presented at 25th Biennial Meeting of the International-Society-for-Neurochemistry Jointly with the 13th Meeting of the Asian-Pacific-Society-for-Neurochemistry in Conjunction with the 35th Meeting of the Australasian-Neuroscience-Society, Cairns, AUSTRALIA, 23 August 2015 - 27 August 2015, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000360206300372&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Goulton C; Moorhouse A, 2015, 'Effects of the KCC2 membrane transporter on neuronal excitability and seizure models in the hippocampal slice preparation', in JOURNAL OF NEUROCHEMISTRY, WILEY-BLACKWELL, Cairns, AUSTRALIA, Vol. 134, pp. 140 - 140, presented at 25th Biennial Meeting of the International-Society-for-Neurochemistry Jointly with the 13th Meeting of the Asian-Pacific-Society-for-Neurochemistry in Conjunction with the 35th Meeting of the Australasian-Neuroscience-Society, Cairns, AUSTRALIA, 23 August 2015 - 27 August 2015, https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000360206300321&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
Patents
Kim Y; Bertrand P; Moorhouse A; Wong ACY; Craig A; Power J; Klugmann M; Krishnan A; Morris R, 2018, Methods for inhibiting neuron apoptosis and necrosis, Patent No. 2013286815, Patent Agent:, https://worldwide.espacenet.com/publicationDetails/biblio?CC=AU&NR=2013286815B2&KC=B2&FT=D
Housley GD; Kim YS; Bertrand PP; Moorhouse AJ; Wong AC; Craig A; Power J; Klugmann M; Krishnan AV; Morris R, 2012, Methods for inhibiting neuron apoptosis and necrosis” (filed by New South Innovations – (UNSW) – Au Provisional Patent Application No. 2012902920, 6 July 2012)., AUSTRALIA, 2012, Patent No. 2012902920, Patent Agent:, status:%20Applied%20for%20(Provisional)%20Registered%20in%20names%20of%20(Inventors)